Makhzoumi devotes much of his time and resources to charitable deeds. In 1997, he founded the Makhzoumi Foundation, a private Lebanese non‐profit organization that contributes through its vocational training, health care and micro‐credit programs, to Lebanese civil society development. The Foundation is currently chaired by Mrs. May Naamani Makhzoumi.

Makhzoumi Foundation developed departments, programs and units to address the needs of the Lebanese community and that of its residents. It does that through improving their socioeconomic status by extending loans, developing skills through informal and formal vocational trainings, providing health awareness while supplying core relief items to the most vulnerable communities, making good value healthcare available, preserving and raising awareness on agro‐environmental issues, empowering youth potentials, and orienting them to achieve self‐sustainability and independence.